from Journal of Occupational Medicine and Environmental Health
E-SMOKING: EMERGING PUBLIC HEALTH PROBLEM in Occupational Medicine ?
MATEUSZ JANKOWSKI1, GRZEGORZ BROŻEK1, JOSHUA LAWSON2, SZYMON SKOCZYŃSKI3, and JAN EUGENIUSZ ZEJDA1 1 Medical University of Silesia in Katowice, Katowice, Poland School of Medicine in Katowice, Department of Epidemiology 2 University of Saskatchewan, Saskatoon, Canada Canadian Center for Health and Safety in Agriculture, Department of Medicine 3 Medical University of Silesia in Katowice, Katowice, Poland School of Medicine in Katowice, Department of Pneumonology
Abstract
E-cigarette use has become increasingly popular, especially among
the young. Its long-term influence upon health is unknown. Aim of
this review has been to present the current state of knowledge
about the impact of e-cigarette use on health, with an emphasis on
Central and Eastern Europe. During the preparation of this
narrative review, the literature on e-cigarettes available within the
network PubMed was retrieved and examined. In the final review,
64 research papers were included. We specifically assessed the
construction and operation of the e-cigarette as well as the
chemical composition of the e-liquid; the impact that vapor arising
from the use of e-cigarette explored in experimental models in
vitro; and short-term effects of use of e-cigarettes on users’ health.
Among the substances inhaled by the e-smoker, there are several
harmful products, such as: formaldehyde, acetaldehyde, acroleine,
propanal, nicotine, acetone, o-methyl-benzaldehyde, carcinogenic
nitrosamines. Results from experimental animal studies indicate the
negative impact of e-cigarette exposure on test models, such as
ascytotoxicity, oxidative stress, inflammation, airway hyper
reactivity, airway remodeling, mucin production, apoptosis, and
emphysematous changes. The short-term impact of e-cigarettes on
human health has been studied mostly in experimental setting.
Available evidence shows that the use of e-cigarettes may result in
acute lung function responses (e.g., increase in impedance,
peripheral airway flow resistance) and induce oxidative stress.
Based on the current available evidence, e-cigarette use is
associated with harmful biologic responses, although it may be less
harmful than traditional cigarettes.
Int J Occup Med Environ Health 2017
Key words: Smoking, Nicotine, Literature review, E-cigarette, Electronic cigarette, Tobacco products
E-SMOKING: EMERGING PUBLIC HEALTH PROBLEM in Occupational Medicine ?
MATEUSZ JANKOWSKI1, GRZEGORZ BROŻEK1, JOSHUA LAWSON2, SZYMON SKOCZYŃSKI3, and JAN EUGENIUSZ ZEJDA1 1 Medical University of Silesia in Katowice, Katowice, Poland School of Medicine in Katowice, Department of Epidemiology 2 University of Saskatchewan, Saskatoon, Canada Canadian Center for Health and Safety in Agriculture, Department of Medicine 3 Medical University of Silesia in Katowice, Katowice, Poland School of Medicine in Katowice, Department of Pneumonology
Abstract
E-cigarette use has become increasingly popular, especially among
the young. Its long-term influence upon health is unknown. Aim of
this review has been to present the current state of knowledge
about the impact of e-cigarette use on health, with an emphasis on
Central and Eastern Europe. During the preparation of this
narrative review, the literature on e-cigarettes available within the
network PubMed was retrieved and examined. In the final review,
64 research papers were included. We specifically assessed the
construction and operation of the e-cigarette as well as the
chemical composition of the e-liquid; the impact that vapor arising
from the use of e-cigarette explored in experimental models in
vitro; and short-term effects of use of e-cigarettes on users’ health.
Among the substances inhaled by the e-smoker, there are several
harmful products, such as: formaldehyde, acetaldehyde, acroleine,
propanal, nicotine, acetone, o-methyl-benzaldehyde, carcinogenic
nitrosamines. Results from experimental animal studies indicate the
negative impact of e-cigarette exposure on test models, such as
ascytotoxicity, oxidative stress, inflammation, airway hyper
reactivity, airway remodeling, mucin production, apoptosis, and
emphysematous changes. The short-term impact of e-cigarettes on
human health has been studied mostly in experimental setting.
Available evidence shows that the use of e-cigarettes may result in
acute lung function responses (e.g., increase in impedance,
peripheral airway flow resistance) and induce oxidative stress.
Based on the current available evidence, e-cigarette use is
associated with harmful biologic responses, although it may be less
harmful than traditional cigarettes.
Int J Occup Med Environ Health 2017
Key words: Smoking, Nicotine, Literature review, E-cigarette, Electronic cigarette, Tobacco products
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